Safiye Emirdag | Organic Chemistry | Best Researcher Award

Assoc. Prof. Dr. Safiye Emirdag | Organic Chemistry | Best Researcher Award

Assoc. Prof. Dr. Safiye Emirdag | Organic Chemistry – Assistant Professor at Ege University, Turkey

Assoc. Prof. Dr. Safiye Emirdağ is a highly accomplished researcher in the field of Organic and Medicinal Chemistry, currently serving at Ege University. Her scientific journey is rooted in the synthesis and evaluation of bioactive natural product derivatives, with a focus on developing potential anticancer and antimicrobial agents. With a dynamic career spanning over two decades, she has combined deep theoretical knowledge with practical application to create impactful research that bridges chemistry and medicine. Her interdisciplinary approach, collaborative efforts, and intellectual contributions continue to push the boundaries of therapeutic molecule design.

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🎓 Education:

Dr. Emirdağ pursued her academic training entirely at Ege University, where she earned both her MSc and PhD in Chemistry, specializing in natural product synthesis. Following her doctoral work, she advanced her expertise through a prestigious postdoctoral fellowship in Green Chemistry at the University of Hohenheim, Germany. This international experience helped shape her environmentally conscious approach to chemical synthesis and expanded her scientific vision toward globally relevant applications.

💼 Experience:

Throughout her professional career, Dr. Emirdağ has held various academic and research roles within Ege University’s Department of Chemistry. From her early involvement in spectroscopic and phytochemical studies to her current leadership in semisynthetic derivative research, she has shown remarkable versatility and dedication. She served as principal investigator and co-investigator in multiple TÜBİTAK, BAP, and EBİLTEM-funded projects, collaborating with national and international institutions, including Kumamoto University in Japan. Her experience extends to reviewing for high-impact journals and evaluating projects for national funding agencies, underlining her scientific credibility and influence.

🔬 Research Interest:

Dr. Emirdağ’s primary research interests lie in Organic Chemistry, Bioorganic Chemistry, and Medicinal Chemistry, with a niche specialization in the semi-synthesis of natural products such as gypsogenin and egonol. Her work aims to design and optimize hybrid molecules for anticancer and antimicrobial applications. She is deeply involved in structure–activity relationship (SAR) studies, enzyme-catalyzed reactions, and the use of spectroscopy (IR, NMR) for compound characterization. Recently, her focus has expanded to include computational tools such as ADME prediction and molecular docking, strengthening the translational aspect of her research.

🏆 Awards and Recognitions:

Dr. Emirdağ’s pioneering research has earned her recognition through national and international project leadership, including bilateral cooperation with Japanese institutions. Her scientific merit has been validated with two granted national patents and one international patent application currently under substantive review. She has contributed to the development of gypsogenin-based hybrid compounds with therapeutic potential and was selected as an evaluator for TÜBİTAK funding schemes—an acknowledgment of her subject-matter authority. Her achievements illustrate both innovation and dedication, qualifying her as a top contender for the Best Researcher Award.

📚 Selected Publications:

  1. 🧪 “Synthesis and antibacterial activity of egonol derivatives” (2008, Bioorganic & Medicinal Chemistry) – Cited by 50+ articles.
  2. 🧬 “Synthesis, antimicrobial and cytotoxic activities of gypsogenin derivatives” (2014, European Journal of Medicinal Chemistry) – Cited by 60+ studies in cancer research.
  3. ⚗️ “Laccase-catalyzed reaction using air as an oxidant” (2013, Tetrahedron) – Pioneered green chemistry methods, cited in enzyme catalysis research.
  4. 🧫 “Design, synthesis and activity evaluation of gypsogenin-based anticancer agents” (2019, Molecules) – Provided novel insights into ABL kinase inhibition, cited by 40+ articles.
  5. 🧿 “EGFR-targeted triterpene analogues for glioma therapy” (2021, International Journal of Molecular Sciences) – Cited by researchers working on glioblastoma treatment.
  6. 🧴 “Anti-neoplastic activity of gypsogenin derivatives” (2014, Bioorganic Chemistry) – Supported preclinical drug discovery pipelines.
  7. 🧠 “Semisynthetic gypsogenin derivatives for leukemia” (2022, International Journal of Biological Macromolecules) – High citation rate due to promising bioactivity.

🔚 Conclusion:

Assoc. Prof. Dr. Safiye Emirdağ stands as a leading figure in the intersection of natural product chemistry and therapeutic innovation. Her research consistently reflects scientific rigor, originality, and translational potential. The blend of synthetic strategy, bioactivity profiling, and interdisciplinary collaboration defines her impactful academic legacy. Her ability to secure patents, publish widely, and foster international ties positions her not just as a researcher, but as a scientific leader. For these reasons, Dr. Emirdağ is exceptionally well-qualified for the Best Researcher Award, and her continued contributions promise further advancements in drug discovery and organic chemistry.

 

 

 

Prof. Dr. Zhixiang Xie | Organic Chemistry | Best Researcher Award

Prof. Dr. Zhixiang Xie | Organic Chemistry | Best Researcher Award

Prof. Dr. Zhixiang Xie | Organic Chemistry – Lanzhou University, China

Professor Zhixiang Xie is a highly accomplished researcher in the field of synthetic organic chemistry, specializing in total synthesis, biomimetic strategies, and advanced reaction methodologies. He has built a reputation for designing and executing complex synthetic routes for bioactive natural products, significantly advancing the understanding of stereoselective and catalytic processes. Over the course of more than twenty years, he has established a prolific academic career marked by innovation, international collaboration, and impactful scholarship. His research not only contributes to fundamental chemistry but also holds broad potential for pharmaceutical and material science applications.

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Education:

Professor Xie’s academic path began with rigorous training in chemical sciences, where he earned both his master’s and doctoral degrees in organic chemistry from a leading Chinese institution. During his early studies, he developed a deep understanding of organic synthesis, chemical reactivity, and mechanistic analysis. These formative years were crucial in shaping his research mindset, enabling him to approach synthetic challenges with a combination of creativity and precision. His formal education laid the foundation for what would become a deeply impactful career in the chemical sciences.

Experience:

Following his doctoral studies, Professor Xie undertook postdoctoral research at one of China’s premier research universities, collaborating with prominent figures in synthetic chemistry. His postdoctoral work further refined his skills in stereoselective synthesis and natural product construction. In the years that followed, he rapidly progressed through academic positions, achieving full professorship. His appointment as a senior visiting fellow at Stanford University allowed him to engage in high-level collaborative research and integrate cutting-edge synthetic strategies from one of the world’s leading laboratories. Throughout his academic tenure, he has supervised numerous graduate students and postdocs, fostering a culture of research excellence.

Research Interest:

Professor Xie’s research interests center around the total synthesis of structurally complex natural products, particularly those with antiviral, anticancer, and neuroprotective activity. He is especially drawn to biomimetic synthesis, where he emulates nature’s strategies to construct intricate molecular frameworks. His work often integrates asymmetric catalysis, C–H activation, photoredox systems, and cascade reactions to achieve highly efficient and selective syntheses. Additionally, he explores the design of new synthetic methodologies for building functional organic molecules, contributing to the fields of medicinal chemistry, sustainable chemistry, and molecular innovation.

Award:

Professor Xie’s exceptional research contributions have been recognized with several national and institutional honors. He was selected for the Program for New Century Excellent Talents in University by the Ministry of Education, a prestigious award recognizing academic leadership and innovation. In recognition of his synthetic achievements, he received the NHU-CJC Innovation Award, honoring his creative breakthroughs in organic synthesis. Furthermore, he has been designated as a Science and Technology Expert in Gansu Province and named a Senior Member of the Chinese Chemical Society, reflecting the broad impact of his scientific contributions across China.

Publication:

📘 Asymmetric total synthesis of benzenoid cephalotane-type diterpenoids (2025), Nature Communications, cited by 25 articles.
🔬 Total Synthesis of Berkeleyone A and Preaustinoid A through Epoxypolyene Cyclization (2025), Angewandte Chemie International Edition, cited by 17 articles.
🧪 Cocrystal of Configurational/Conformational Isomers in Energetic Materials (2025), Journal of Organic Chemistry, cited by 10 articles.
🌿 Scalable Total Synthesis of (+)- and (–)-Codonopiloneolignanin A (2021), Organic Letters, cited by 43 articles.
🔍 Biomimetic Synthesis of Psiguajdianone (2019), Organic Letters, cited by 58 articles.
⚗️ Visible-Light-Induced Charge Transfer Enables Csp³–H Functionalization (2020), Organic Letters, cited by 61 articles.
🧬 Enantioselective aerobic oxidative coupling of glycine derivatives (2020), Chemical Science, cited by 48 articles.

Conclusion:

Professor Zhixiang Xie is a leading researcher whose career exemplifies excellence in innovation, scholarship, and academic leadership. His groundbreaking work in synthetic organic chemistry continues to expand the frontiers of the discipline, offering new tools, frameworks, and insights that have applications far beyond the laboratory. With a strong record of publications, respected awards, and a commitment to training the next generation of scientists, Professor Xie is an ideal candidate for the Best Researcher Award. His work not only contributes to the advancement of chemistry but also resonates with the mission of fostering impactful and transformative scientific research.