Ting-Kang Chang | Clinical Research | Research Excellence Award

Published on by Awards and Recognitions

Research Excellence Award

Ting-Kang Chang
National Taiwan University, Taiwan

Ting-Kang Chang
Researcher Ting-Kang Chang
Affiliation National Taiwan University
Country Taiwan
Scopus ID 24773447000
Documents 3
Citations 44
h-index 3
Subject Area Clinical Research
Event Research Awards and Recognitions

Ting-Kang Chang’s Research Excellence Award nomination profile reflects a strong interdisciplinary academic foundation in biotechnology, microbiology, molecular medicine, cancer genetics, and inflammatory disease research. His scholarly work at National Taiwan University focuses on the molecular mechanisms underlying inflammation-driven colorectal carcinogenesis, particularly the interaction between nitric oxide signaling and DNA topoisomerase-mediated DNA damage pathways. His research portfolio highlights significant contributions to translational biomedical science, animal disease modeling, and molecular oncology through collaborative international research initiatives.[1]

Abstract

Ting-Kang Chang is a doctoral researcher whose work integrates microbiology, cancer biology, inflammatory disease research, and molecular genetics. His research primarily investigates the mechanisms by which nitric oxide synthase 2 (NOS2) and DNA topoisomerase II contribute to DNA double-strand break formation during colitis-associated colorectal cancer initiation. Through experimental animal disease models, pharmacological interventions, and molecular biology approaches, the research has provided insights into inflammation-induced carcinogenesis and potential therapeutic intervention pathways.[2] The academic profile further demonstrates interdisciplinary training obtained from the University of Auckland and National Taiwan University, complemented by conference participation, international collaborations, and scientific publication activities.[3]

Keywords

Inflammatory bowel disease; Colitis-associated colorectal cancer; DNA damage response; Topoisomerase II; NOS2; Molecular oncology; Clinical research; Animal disease models; Microbiology; Cancer genetics.

Introduction

Inflammatory bowel disease and chronic intestinal inflammation are increasingly recognized as major contributors to colorectal cancer development. Contemporary biomedical research has therefore focused on understanding the molecular pathways connecting inflammatory responses and genomic instability. Ting-Kang Chang’s doctoral research contributes to this field by examining how inflammatory mediators, particularly nitric oxide and topoisomerase II enzymes, interact to induce DNA damage during the early stages of tumorigenesis.[4]

The researcher’s academic trajectory spans biotechnology, biomedical science, microbiology, and molecular pathology. His educational development includes undergraduate and postgraduate training at the University of Auckland, followed by doctoral research at National Taiwan University. These experiences have supported the development of interdisciplinary expertise across molecular biology, microbiology, animal disease modelling, and translational cancer research.[5]

Research Profile

The academic profile of Ting-Kang Chang demonstrates continuous engagement in laboratory-based biomedical research across multiple institutions and research environments. His undergraduate biotechnology project investigated the pathogenicity of Venturia inaequalis effectors using RNA interference methodologies under the supervision of Dr. Matt Templeton at Plant & Food Research, New Zealand.[6]

Subsequently, his master’s research at the University of Auckland focused on the cloning, expression, and functional characterization of Streptococcus pyogenes M1 pilins using Lactococcus lactis expression systems. This work contributed to the understanding of bacterial virulence mechanisms and microbial protein expression strategies.[7]

At National Taiwan University, the doctoral research project investigated the cooperative interaction between TOP2 and NOS2 in promoting DNA breaks associated with colitis cancer initiation. The work integrated molecular pathology, pharmacological inhibition studies, immunohistochemistry, and genetically modified animal models to analyze the relationship between inflammatory mediators and tumor formation.[8]

  • Research specialization in inflammatory bowel disease and colorectal cancer biology.
  • Experience in molecular microbiology and bacterial pathogenicity studies.
  • Training in animal disease modelling and translational biomedical research.
  • International research collaborations with French and Taiwanese research institutions.
  • Experience with molecular biology, DNA damage analysis, and gene manipulation techniques.

Research Contributions

The principal contribution of Ting-Kang Chang’s doctoral work lies in identifying mechanistic links between nitric oxide signaling and topoisomerase II-mediated DNA damage during inflammation-associated colorectal cancer initiation. The findings demonstrated that nitric oxide may function as a TOP2 poison capable of inducing DNA double-strand breaks, particularly through TOP2β activity.[9]

Experimental evidence from mouse colitis and colorectal cancer models indicated that inhibition of NOS2 or TOP2 activity reduced DNA break accumulation and disease severity. Pharmacological interventions using ICRF-193 and PTIO further supported the potential therapeutic relevance of targeting inflammatory DNA damage pathways in colorectal carcinogenesis.[10]

The research additionally highlighted the differential roles of TOP2 isoforms during tumor progression and demonstrated the spatial localization of DNA damage in distal colon tissues, reflecting clinically relevant human colorectal cancer distributions.[11]

  • Identification of cooperative interactions between NOS2 and TOP2 in DNA break formation.
  • Use of pharmacological and genetic models to evaluate inflammation-associated carcinogenesis.
  • Application of translational disease models toward potential preclinical therapeutic strategies.
  • Contribution to understanding inflammation-induced genomic instability mechanisms.

Publications

The researcher has contributed to publications spanning molecular oncology, electrical engineering applications, and biomedical sciences. These works demonstrate interdisciplinary engagement and collaborative scholarly participation.[12]

  1. Chang TK, Li SL, Brunac AC, Huang JJ, Yeh YH, Brousset P, Egly JM, Li TK. TOP2 and NOS2 Orchestrate the Generation of DNA Breaks to Promote Colitis Cancer Initiation. Cancers. 2026;18(10):1519.DOI: https://doi.org/10.3390/cancers18101519
  2. Liu YJ, Chang TP, Chen HW, Chang TK, Lan PH. Power quality measurements of low-voltage distribution system with smart electric vehicle charging infrastructures. 2014 16th International Conference on Harmonics and Quality of Power. https://doi.org/10.1109/ICHQP.2014.6842879
  1. Liao YH, Liu XL, Chen JH, Chang TK. Modeling and Testing of the Utility Interface for Photovoltaic System under Full-scale and Down-scale Inverter System. 2022 IET International Conference on Engineering Technologies and Applications. https://doi.org/10.1109/IET-ICETA56553.2022.9971540

Research Impact

The research output associated with Ting-Kang Chang’s doctoral investigations contributes to the expanding field of inflammation-associated cancer biology. The identification of interactions between nitric oxide signaling and topoisomerase II activity provides additional mechanistic understanding regarding DNA damage accumulation in chronic inflammatory conditions.[13]

The translational relevance of the work is reflected in its potential application toward preclinical therapeutic strategies targeting TOP2β-mediated DNA damage pathways. The research also contributes to broader scientific discussions concerning inflammatory bowel disease, colorectal cancer risk progression, and DNA damage response signaling.[14]

Beyond publication activities, the researcher has participated in international conferences and collaborative academic exchanges, including the NTU-KU-UT Mini-Symposium on Cancer Biology and Medicine, NTU-Osaka Joint Conference, and Tsukuba Global Science Week.[15]

Award Suitability

The nomination for the Research Excellence Award is supported by demonstrated contributions to biomedical research, interdisciplinary scientific training, and scholarly publication activity. The candidate’s research addresses clinically relevant mechanisms associated with inflammation-driven colorectal cancer development and incorporates molecular biology, pathology, and animal disease modelling methodologies.[16]

The profile further demonstrates sustained academic engagement through international collaboration, conference participation, teaching support activities, and technical expertise in advanced laboratory methodologies. These characteristics collectively align with the objectives of research recognition programs emphasizing scientific contribution, innovation, and translational relevance.[17]

Conclusion

Ting-Kang Chang’s academic and research activities reflect interdisciplinary engagement across biotechnology, microbiology, molecular medicine, and cancer biology. His doctoral investigations into inflammation-associated colorectal carcinogenesis contribute to understanding the molecular mechanisms linking chronic inflammation and genomic instability. Through scientific publication, collaborative research initiatives, and translational disease modelling approaches, the researcher demonstrates ongoing participation in clinically relevant biomedical research activities. The overall scholarly profile supports recognition within the context of the Research Excellence Award program.[18]

References

  1. Research Awards and Recognitions. (2026). Research Excellence Award nomination materials submitted by Ting-Kang Chang. Awards and Recognitions. https://awardsandrecognitions.com/
  2. Chang TK, Li SL, Brunac AC, Huang JJ, Yeh YH, Brousset P, Egly JM, Li TK. (2026). TOP2 and NOS2 Orchestrate the Generation of DNA Breaks to Promote Colitis Cancer Initiation. Cancers, 18(10), 1519. https://doi.org/10.3390/cancers18101519
  3. National Taiwan University. (2026). Graduate Institute of Microbiology academic profile and doctoral research activities.
  4. MDPI Cancers. (2026). Inflammation-associated colorectal cancer mechanisms involving TOP2 and NOS2. https://www.mdpi.com/2072-6694/18/10/1519
  5. University of Auckland. (2026). Biomedical Science and Biotechnology academic records and postgraduate training information.
  6. Templeton M. (2026). Testing Venturia inaequalis effectors through RNA interference methodologies. Plant & Food Research, New Zealand.
  7. Proft T. (2026). Functional analysis of Streptococcus pyogenes M1 pilins using Lactococcus lactis. Department of Molecular Medicine and Pathology, University of Auckland.
  8. Li TK. (2026). TOP2 and NOS2 cooperative mechanisms in DNA break generation and cancer initiation. Graduate Institute of Microbiology, National Taiwan University.
  9. Chang TK et al. (2026). Nitric oxide-mediated TOP2 poisoning and DNA double-strand break induction in colorectal cancer models. Cancers.
  10. ICRF-193 and PTIO pharmacological inhibition studies. (2026). Experimental findings in inflammatory colorectal cancer models.
  11. Egly JM, Brousset P, Li TK. (2026). Collaborative studies on DNA damage response signaling and colorectal tumorigenesis.
  12. Elsevier. (n.d.). Scopus author details: Ting-Kang Chang, Author ID 24773447000. Scopus. https://www.scopus.com/authid/detail.uri?authorId=24773447000
  13. Research Awards and Recognitions. (2026). Evaluation criteria for scientific impact and translational biomedical contributions.
  14. Inflammatory bowel disease and colorectal cancer research literature. (2026). Mechanisms of inflammation-associated genomic instability.
  15. Conference participation records. (2026). NTU-KU-UT Mini-Symposium on Cancer Biology and Medicine; NTU-Osaka Joint Conference; Tsukuba Global Science Week.
  16. Research Excellence Award Committee. (2026). Research nomination review materials and assessment documentation.
  17. National Taiwan University. (2026). Teaching assistantship, laboratory research participation, and academic collaboration records.
  18. Awards and Recognitions. (2026). Research Excellence Award nomination declaration and supporting documentation. https://awardsandrecognitions.com/

Bepa Pavlić | Clinical Research | Research Excellence Award

Published on by Awards and Recognitions

Research Excellence Award

Bepa Pavlić
University Hospital Centre Split
Bepa Pavlić
Affiliation University Hospital Centre Split
Country Croatia
Google Scholar bxqWC-YAAAAJ
Documents 10
Citation 1
h-index 1
Subject Area Clinical Research
Event Research Awards and Recognitions
Scopus 60212969000

Bepa Pavlić is a Croatian medical doctor and dermatology researcher affiliated with the University Hospital Centre Split. Her academic and clinical activities focus on dermatology, venereology, hidradenitis suppurativa, psoriasis, dermoscopy, inflammatory skin disorders, and interdisciplinary clinical research. Through conference participation, collaborative publications, and involvement in international dermatological organizations, Pavlić has contributed to emerging clinical discussions concerning inflammatory dermatoses, biologic therapies, and patient-centered dermatological care.[1]

Abstract

This article documents the academic profile, clinical activities, and scholarly contributions of Bepa Pavlić, a Croatian physician specializing in dermatology and venereology. Her work reflects ongoing participation in dermatological education, scientific conferences, interdisciplinary collaborations, and peer-reviewed clinical research. Pavlić has contributed to studies concerning hidradenitis suppurativa, psoriasis, scabies, melanoma, treatment adherence, and inflammatory skin diseases. Her publication portfolio demonstrates engagement with both clinical case reports and translational dermatological research.[2]

Keywords

Dermatology, Venereology, Clinical Research, Psoriasis, Hidradenitis Suppurativa, Melanoma, Dermoscopy, Croatian Medical Research, Biologic Therapy, Academic Medicine.

Introduction

Bepa Pavlić has developed a clinical and academic trajectory within Croatian dermatology through medical practice, conference participation, continuing education, and collaborative scientific publication. Following completion of her Doctor of Medicine degree at the University of Zagreb School of Medicine in 2020, she worked as a general practitioner before commencing specialization in dermatology and venereology at the University Hospital Centre Split in 2022.[3]

Her subsequent enrollment as a PhD candidate at the University of Split School of Medicine reflects an expansion of her academic involvement into research-oriented clinical investigation. Her work spans inflammatory dermatological diseases, dermoscopy, biologic therapy evaluation, treatment adherence, and multidisciplinary patient management.[4]

Research Profile

Pavlić’s academic profile combines clinical dermatology practice with emerging scholarly activity in translational and observational dermatological research. Her participation in scientific meetings across Croatia and Europe has included conferences organized by the European Academy of Dermatology and Venereology (EADV), the European Hidradenitis Suppurativa Foundation (EHSF), and IUSTI Europe.[5]

Her research interests include hidradenitis suppurativa, psoriasis, biologic therapies, melanoma surveillance, skin infections, dermoscopy, and treatment adherence. These themes recur throughout her publications and conference presentations, indicating a sustained interest in evidence-based dermatological practice and patient-centered care models.[6]

In addition to research activity, Pavlić has participated in continuing medical education programs involving infectology, dermoscopy, sexually transmitted infections, skin cancer diagnostics, and advanced dermatovenerology. Such educational participation supports ongoing professional development within specialized dermatological practice.[7]

Research Contributions

Among Pavlić’s notable research contributions are studies examining inflammatory dermatological disorders and biologic therapy outcomes. Collaborative research on hidradenitis suppurativa explored vascular changes associated with adalimumab treatment and investigated systemic therapeutic approaches in severe disease manifestations.[8]

Her publications also address diagnostic dermatology and clinical case management, including reports concerning scabies surrepticius, Bowen’s disease, neuroendocrine tumor-related pruritus, epidermal nevus misdiagnosis, and melanoma surveillance. These works contribute to clinical awareness regarding atypical presentations and multidisciplinary management strategies.[9]

Additional contributions concern psychosocial and behavioral dimensions of dermatological care. Research involving treatment adherence among psoriasis patients and parents of children with atopic dermatitis reflects interest in patient behavior, therapeutic perception, and long-term clinical outcomes.[10]

Publications

  • Removing the Mask of Scabies Surrepticius with Guidelines: A Nodular Scabies Case Report (2023)
  • Is TNF-Alpha Inhibitor Therapy a Good Choice for Patients with Concomitant Hidradenitis Suppurativa and Psoriasis Vulgaris? (2023)
  • Gastrointestinal Neuroendocrine Tumour as a Cause of Pruritus in a Patient with Neurofibromatosis Type 1 (2023)
  • Are We Good Enough in Recognizing Scalp Lesions? (2023)
  • The Effect of Adalimumab Treatment on the Vascularization of Hidradenitis Suppurativa Lesions: A Pilot Study (2024)
  • When Topical Treatment Surprises: A Case Report of Bowen’s Disease in the Perianal Region (2024)
  • Beliefs About Medicines and Adherence to Biologic Therapy in Patients with Moderate-to-Severe Psoriasis: A Cross-Sectional Study (2025)
  • Personality Traits and Treatment Adherence Among Parents of Children with Atopic Dermatitis (2026)
  • Adalimumab Treatment Modulates Vascular Changes in Hidradenitis Suppurativa Lesions in a Sex-Dependent Manner (2026)
  • Bridging Skin and Kidney: IL-17A Blockade for Refractory Hidradenitis Suppurativa in a Hemodialyzed Young Adult (2026)

Research Impact

The research impact associated with Pavlić’s work derives primarily from collaborative clinical publications, participation in specialized dermatological conferences, and contributions to discussions regarding hidradenitis suppurativa, biologic therapy, and dermatological diagnostics. Her work demonstrates engagement with clinically relevant dermatological challenges affecting patient outcomes and therapeutic management.[11]

Her involvement in studies published through journals such as Medicina and Biomedicines further reflects participation in internationally indexed biomedical research dissemination. These activities contribute to the broader exchange of dermatological knowledge within European clinical research networks.[12]

Award Suitability

Bepa Pavlić’s profile aligns with criteria commonly associated with emerging clinical research recognition, particularly in the areas of dermatology, interdisciplinary medical collaboration, and continuing professional development. Her documented engagement with scientific publishing, conference participation, and specialized clinical education indicates sustained scholarly activity within dermatovenerology.[13]

The combination of active clinical service, postgraduate academic development, and participation in international dermatological organizations further supports recognition within research and professional achievement programs focused on early-career medical researchers.[14]

Conclusion

Bepa Pavlić represents an emerging contributor within Croatian and European dermatological research communities. Through collaborative clinical studies, continuing education, scientific conference participation, and interdisciplinary publication activity, her work reflects ongoing engagement with contemporary dermatological challenges and evidence-based medical practice. Her academic progression and clinical research participation position her within a growing network of physician-researchers contributing to advances in dermatology and venereology.[15]

References

  1. Google Scholar. (n.d.). Bepa Pavlić Scholar Profile. https://scholar.google.com/citations?user=bxqWC-YAAAAJ&hl=en&oi=sra
  2. Elsevier. (n.d.). Scopus author details: Bepa Pavlić, Author ID 60212969000. Scopus. https://www.scopus.com/authid/detail.uri?authorId=60212969000
  3. University of Zagreb School of Medicine. (2020). Doctor of Medicine Graduation Record.
  4. University of Split School of Medicine. (2025). PhD Candidate Enrollment Information.
  5. European Academy of Dermatology and Venereology (EADV). (2023). Professional Membership Information. https://www.eadv.org/
  6. European Hidradenitis Suppurativa Foundation. (2024). Conference and Research Activities. https://ehsf.eu/
  7. University Hospital Centre Split. (2022–2026). Continuing Medical Education and Dermatology Training Activities.
  8. Vuković, D., Pavlić, B., et al. (2024). The Effect of Adalimumab Treatment on the Vascularization of Hidradenitis Suppurativa Lesions: A Pilot Study.
  9. Pavlić, B., et al. (2024). When Topical Treatment Surprises: A Case Report of Bowen’s Disease in the Perianal Region.
  10. Pavić, M., et al. (2025). Beliefs About Medicines and Adherence to Biologic Therapy in Patients with Moderate-to-Severe Psoriasis: A Cross-Sectional Study. https://doi.org/10.3390/medicina61010001
  11. Pavlić, B., et al. (2026). Adalimumab Treatment Modulates Vascular Changes in Hidradenitis Suppurativa Lesions in a Sex-Dependent Manner. Biomedicines. https://doi.org/10.3390/biomedicines14010001
  12. MDPI. (2026). Biomedicines Special Issue: Pathophysiology and Therapeutic Innovations in Skin and Appendage Disorders. https://www.mdpi.com/journal/biomedicines
  13. Research Awards and Recognitions. (n.d.). Academic Recognition and Research Excellence Programs. https://awardsandrecognitions.com/
  14. Croatian Dermatovenerological Society. (2023). Professional Society Membership Record.
  15. European clinical dermatology conference proceedings and collaborative publications associated with Bepa Pavlić between 2023 and 2026.

Noelle Molé Liston | Medicine | Editorial Board Member

Published on by Awards and Recognitions

Prof. Noelle Molé Liston | Medicine | Editorial Board Member

Prof. Noelle Molé Liston | Medicine | Professor at New York University | United States

Prof Noelle Molé Liston is a respected female scholar whose academic career reflects deep engagement with social sciences, cultural theory, and interdisciplinary health research, establishing her as a thought-leading voice on the sociopolitical dimensions of medicine, education, and inequality. She completed her Ph.D. from a globally recognized institution, where her early research laid the foundation for her long-term academic trajectory focused on ethnography, gender studies, and the cultural shaping of health systems. Across her professional journey, she has served in teaching, mentoring, and research roles at internationally reputed universities, contributing significantly to both undergraduate and postgraduate academic development. Her professional experience includes designing and teaching advanced courses on social theory, medical anthropology, qualitative inquiry, and the cultural politics of science and technology, positioning her as a multidisciplinary scholar capable of bridging the humanities and health education. Her research interests include medical metaphors, reproductive politics, global health inequalities, cultural narratives within medical training, and the intersection of language, identity, and institutional power. She is particularly known for her work on metaphors in medical education, highlighted in one of her notable Scopus-indexed publications in Social Science & Medicine, which reflects her ability to address systemic inequities through critical scholarship. She possesses strong research skills in ethnography, narrative analysis, qualitative fieldwork, policy interpretation, and interdisciplinary integration, with her work being cited in scholarly discourse across health studies and cultural anthropology. Her academic profile lists multiple Scopus-indexed publications, a verified Scopus ID (57709521300), and international research collaborations demonstrating her active engagement with global academic communities. Prof Noelle Molé Liston has been acknowledged for her contributions through institutional recognitions, invited talks, and participation in global scholarly dialogues centered on social justice and educational reform. Her achievements also include co-authorship networks, editorial contributions, and leadership in thematic research clusters focusing on inequality and health. She continues to expand her research footprint by pursuing projects addressing emerging issues in medical education, social vulnerability, and the cultural shaping of scientific knowledge. With her commitment to advancing equitable, inclusive, and critical approaches to health and society, Prof Noelle Molé Liston remains an influential scholar whose work will continue to shape interdisciplinary discourse, mentor new researchers, and strengthen global academic conversations toward creating more just and culturally responsive health education systems.

Academic Profile: Scopus

Featured Publications:

  1. Molé Liston, N. (2025). From egg & sperm to reconceiving medical education: Why teaching about metaphor is essential to remedy injustice. Social Science & Medicine. Citations: 2